Weight Management Study

Obesity and overweight are complex, long-term conditions affecting millions of Australians. They can place significant strain on the body — contributing to high blood pressure, sleep apnoea, high cholesterol, and cardiovascular disease — as well as impacting energy, confidence, and day-to-day quality of life.

While healthy eating, physical activity, and behavioural support are important foundations of weight management, many people find that long-term weight loss is difficult to achieve and sustain. This study is exploring whether a once-weekly injectable treatment can provide meaningful, sustained support for weight management over time, by targeting pathways involved in appetite, eating behaviour, and metabolic regulation.

People with prediabetes are welcome to apply. If you have prediabetes at the start of the study, you may be invited to take part in an extended participation period, with the aim of understanding whether the treatment may also help delay or reduce progression to type 2 diabetes.

This trial is enrolling now in our Ipswich site. Register your interest now and our team will contact you.

• Living with obesity with a BMI of 30 or above — OR —
• Overweight with a BMI of 27 or above AND have at least one weight-related health condition such as high blood pressure, high cholesterol, sleep apnoea, or cardiovascular disease
• Do not have a diagnosis of type 2 diabetes (people with prediabetes may still be eligible)

Not sure if you qualify? Register your interest anyway. Our team will help you understand if this study is a fit — no commitment required.

Note: Participants will be randomly assigned to receive either the investigational once-weekly injection or a placebo. All participants will also receive lifestyle guidance on healthy eating and physical activity.

• Once open, you will be invited for a screening visit including fasting blood tests, weight and height measurement, and a health history review
• More frequent visits in the early phase — every 4 weeks — reducing to every 12 weeks after the initial period
• Weight checks, blood tests, and quality of life questionnaires at each visit
• Lifestyle guidance sessions on healthy eating and physical activity throughout the study
• All study medications, tests, and consultations provided at no cost to you
• Reimbursement for your time and reasonable travel costs per visit

New treatment option: Gain early access to an investigational weight management treatment at no cost.

Expert support: Receive lifestyle guidance and regular health monitoring from our clinical team throughout.

Reimbursement: All clinic visits are reimbursed for your time and reasonable travel costs.

Help others: Contribute to research that may help others living with obesity or overweight in the future.

Footer note: Your privacy is important. All personal information will be kept strictly confidential.

This study is enrolling at our Ipswich site. To register your interest:

• Complete the online expression of interest form below OR
• Call our team directly on (07) 3180 8045

Once you register, a member of our clinical team will contact you to discuss the study in more detail, answer any questions, and confirm whether you may be eligible for a screening visit.